RNA - Genetherapys
Who we are - Spoke 9


University of Milan (P.I. Paolo Ciana) boasts internationally recognized technical and scientific expertise in preclinical and clinical pharmacology, particularly focusing on biotech drugs. The research groups excel in developing innovative experimental models for in vitro and in vivo studies (zebrafish and mice), with a well-recognized expertise in toxicology and immunology. The affiliate researchers organize and participate across a large interdisciplinary national and international network dedicated to drug research and development, molecular biology, and genetics. Furthermore, they maintain strong collaborations with both international and national biotech and pharmaceutical companies. The University of Milan has an experienced Technology Transfer Office (TTO) that provides vital support for the translation of biomedical research. Finally, the pharmacological expertise includes clinical pharmacology that enjoys close interactions with regulatory bodies within the European Union and throughout Italy.

Tommaso Bellini
Full professor

Dipartimento di Biotecnologie Mediche e Medicina Traslazionale

Paolo Ciana
Full professor

Dipartimento di Scienze della Salute

Emilio Clementi
Full professor

Dipartimento di Scienze Biomediche e Cliniche

Emanuela Corsini
Full professor

Dipartimento di Scienze Farmacologiche e Biomolecolari

Luca Del Giacco
Associate professor

Dipartimento di Bioscienze

Jens Albrecht Ernst Geginat
Associate professor

Dipartimento di Scienze Cliniche e di Comunità

Davide Lecca
Associate professor

Dipartimento di Scienze Farmaceutiche

Massimo Locati
Full professor

Dipartimento di Biotecnologie Mediche e Medicina Traslazionale

Marina Marinovich
Full professor

Dipartimento di Scienze Farmacologiche e Biomolecolari

Domenico Mavilio
Full professor

Dipartimento di Biotecnologie Mediche e Medicina Traslazionale

Paola Minghetti
Full professor

Dipartimento di Scienze Farmaceutiche

Umberto Musazzi
Researcher RTD

Dipartimento di Scienze Farmaceutiche

Luisa Ottobrini
Associate professor

Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti

Massimiliano Pagani
Full professor

Dipartimento di Biotecnologie Mediche e Medicina Traslazionale

Cristiana Perrotta
Associate professor

Dipartimento di Scienze Biomediche e Cliniche

Giulio Pompilio
Full professor

Dipartimento di Scienze Biomediche, Chirurgiche ed Odontoiatriche

Camilla Recordati
Researcher RTD

Dipartimento di Medicina Veterinaria e Scienze Animali

Sara Sattin
Associate professor

Dipartimento di Chimica

Giorgio Scita
Full professor

Dipartimento di Oncologia ed Emato-Oncologia

Pierfausto Seneci
Associate professor

Dipartimento di Chimica

Giuseppe Testa
Full professor

Dipartimento di Oncologia ed Emato-Oncologia

Elisabetta Vegeto
Associate professor

Dipartimento di Scienze Farmaceutiche

Mussadir Khan
Phd student

Dipartimento di Scienze della Salute

Alessia Panzeri
Phd student

Dipartimento di Scienze della Salute

Electra Athena Salome Brunialti
Researcher RTD-A

Dipartimento di Scienze della Salute

Gloria Melzi
Researcher RTD-A

Dipartimento di Scienze Farmacologiche e Biomolecolari

Leonardo Barzaghi
Research Fellow

Dipartimento di Oncologia ed Emato-Oncologia

Gaetano Cannavale
Research Fellow

Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti

Andrea Cappelleri
Research Fellow

Dipartimento di Medicina Veterinaria e Scienze Animali

Alberto Diana
Research Fellow

Dipartimento di Bioscienze

Marco Tullio Rigoli
Research Fellow

Dipartimento di Oncologia ed Emato-Oncologia

Lorenzo Taiarol
Research Fellow

Dipartimento di Scienze Farmaceutiche

Hong Lien Tran
Research Fellow

Dipartimento di Scienze Farmaceutiche

Luca Casiraghi
Technologist

Dipartimento di Biotecnologie Mediche e Medicina Traslazionale

Lorenzo Drufuca
Technologist

Dipartimento di Biotecnologie Mediche e Medicina Traslazionale

Carsten Schulte
Technologist

Dipartimento di Scienze Biomediche e Cliniche

Sara Manellari
Technologist

Dipartimento di Scienze Farmaceutiche

Letizia Venturini
Technologist

Dipartimento di Biotecnologie Mediche e Medicina Traslazionale


National Research Council of Italy – CNR (coordinator Daniele Catalucci).
CNR participants possess expertise in studying the molecular mechanisms underlying the synapse dysfunction and the influence of immune molecules on this process to identify new targets suitable for innovative treatments. CNR studies also include exploring the molecular mechanisms underlying the contractility/relaxation of cardiomyocytes and the formulation of biomimetic nanoparticles for the targeted delivery of specific drugs to the heart.

Maria Rosaria Matarazzo
Research Manager

Istituto di genetica e biofisica “Adriano Buzzati Traverso” (CNR – IGB)

Maria Luisa Malosio
Researcher RTD-A

CNR – Istituto di Neuroscienze (CNR – IN)

Bianca Ambrogina Silva
Researcher

CNR – Istituto di Neuroscienze (CNR – IN)

Marianna Leonzino
Researcher

CNR – Istituto di Neuroscienze (CNR – IN)

Matteo Fossati
Researcher

CNR – Istituto di Neuroscienze (CNR – IN)

Michela Matteoli
Full Professor

CNR – Istituto di Neuroscienze (CNR – IN)

Chiara Adriana Elia
Researcher RTD

CNR – Istituto di Neuroscienze (CNR – IN)

Antonella Borreca
Researcher

CNR – Istituto di Neuroscienze (CNR – IN)

Ibrahim Raya
Phd student

CNR – Istituto di Neuroscienze (CNR – IN)

Daniele Catalucci
Research Manager

Istituto di Ricerca Genetica e Biomedica (CNR – IRGB)

Marie-Louise Bang
Researcher RTD-A

Istituto di Ricerca Genetica e Biomedica (CNR – IRGB)

Elisa Di Pasquale
Researcher RTD-A

Istituto di Ricerca Genetica e Biomedica (CNR – IRGB)

Jessica Modica
Researcher RTD

Istituto di Ricerca Genetica e Biomedica (CNR – IRGB)

Giovanna Mancini
Research Manager

Istituto per i Sistemi Biologici (CNR – ISB)

Francesca Ceccacci
Researcher

Istituto per i Sistemi Biologici (CNR – ISB)


Humanitas University – HUNIMED (coordinators Michela Matteoli and Simona Lodato).
HUNIMED participants investigate neurodevelopment, neurodegenerative, and psychiatric diseases. The affiliate possesses established expertise in iPS-derived brain cells, 3D brain organoids, and RNA drugs, which potentially target complex CNS diseases. Additionally, HUNIMED has extensive experience in RNA drug delivery within the Central Nervous System (CNS) in animal models using various methodologies, as well as in modelling the blood-brain barrier through microfluidics and lab-on-chip systems.

Andrea Gerardo Antonio Lania
Full professor

Riccardo Fesce
Full professor

Roberto Rusconi
Associate professor

Davide Pozzi
Researcher RTD-B

Michela Matteoli
Full professor

Simona Lodato
Associate professor

Elevezia Maria Paraboschi
Researcher RTD-A

Francesco Bolzoni
Researcher RTD-A

Sebastiano Bariselli
Researcher RTD-A

Federica Airi
PhD student

Riccardo Grassi
PhD student

Davide Franzone
PhD student


University of Naples Federico II – UNINA (Coordinator: Angelo Izzo).
UNINA participants possess extensive expertise in developing 2D/3D models and organoids (including EMT, methylomics, and transcriptomics) as well as transgenic models for studying pharmacodynamics, efficacy, and organ/systemic toxicity. Animal models are available for various conditions including cardiovascular and metabolic diseases, inflammation, cancer, dermatology, skeletal muscle diseases, neuropharmacology, respiratory, and gastrointestinal pharmacology/toxicology. Additionally, a UNINA research group specializes in creating pharmacoeconomic models and frameworks for building regulatory reimbursement models using Real-World Evidence (RWE).

Giuseppe Cirino
Full professor

Dipartimento di Farmacia

Claudia Cristiano
Researcher RTD-A

Dipartimento di Farmacia

Geppino Falco
Full professor

Dipartimento di Biologia

Angelo Antonio Izzo
Full professor

Dipartimento di Farmacia

Barbara Majello
Full professor

Dipartimento di Biologia

Rosaria Meli
Full professor

Dipartimento di Farmacia

Valentina Orlando
Researcher RTD-B

Dipartimento di Farmacia

Claudio Pirozzi
Researcher RTD-A

Dipartimento di Farmacia

Barbara Romano
Associate professor

Dipartimento di Farmacia

Pasquale Rapacciuolo
Research Fellow

Dipartimento di Farmacia

Rebecca Amico
PhD student

Dipartimento di Farmacia

Camilla Esposito
PhD student

Dipartimento di Farmacia

Carmen De Caro
Researcher RTD-A

Dipartimento di Farmacia

Paola De Cicco
Researcher RTD-A

Dipartimento di Farmacia


University of Padua – UNIPD (Coordinator: Marisa Brini).
The UNIPD group enjoys international recognition for having developed SPLITS reporters for microscopy applications to map organelle contact sites both in vitro and in vivo. This expertise is essential for leveraging split-Green Fluorescent Protein (GFP) technology in testing the efficiency of nucleic acid-based therapies. Additionally, the group possesses well-established skills in isolating, characterizing, and applying extracellular vesicles in drug therapy, along with expertise in conducting clinical assays to assess the toxicity of gene therapy with a particular expertise for liver toxicity.

Paolo Angeli
Full professor

Dipartimento di Medicina

Luca Bonadies
Researcher RTD-A

Dipartimento della Salute della Donna e del Bambino

Marisa Brini
Full professor

Dipartimento di Scienze del Farmaco

Tito Calì
Associate professor

Dipartimento di Scienze Biomediche

Marco Di Pascoli
Associate professor

Dipartimento di Medicina

Michela Pozzobon
Researcher RTD-B

Dipartimento della Salute della Donna e del Bambino

Margherita Zen
Associate professor

Dipartimento di Medicina

Adamantia Deligiannopoulou
PhD student

Dipartimento di Scienze Biomediche

Celeste Milani
PhD student

Dipartimento di Biologia

Raquel Moll-Diaz
PhD student

Dipartimento della Salute della Donna e del Bambino

Caterina Peggion
Researcher RTD-A

Dipartimento di Biologia

Laura Rigon
Researcher RTD-A

Dipartimento di Medicina


University of Pavia – UNIPV (Coordinator: Maria Cristina Bonferroni).
UNIPV participants possess extensive expertise in the utilization of natural polymers in drug delivery, particularly for treating local infections and promoting tissue repair, while also assessing safety profiles. Additionally, the affiliate offers several models for testing RNA drugs and their carriers, with specific expertise in neuroinflammation.

Maria Cristina Bonferoni
Full professor

Dipartimento di Scienze del Farmaco

Mauro Freccero
Full professor

Dipartimento di Chimica

Piersandro Pallavicini
Full professor

Dipartimento di Chimica

Sara Perteghella
Researcher RTD-B

Dipartimento di Scienze del Farmaco

Marco Peviani
Associate professor

Dipartimento di Biologia e Biotecnologie

Sara Tengattini
Researcher RTD-A

Dipartimento di Scienze del Farmaco

Cristina Travelli
Associate professor

Dipartimento di Scienze del Farmaco

Daniela Buonocore
Researcher RTD-A

Dipartimento di Biologia e Biotecnologie

Rachele Rossi
Phd student

Dipartimento di Scienze del Farmaco


Sapienza University of Rome UNIROMA1 (Coordinator: Arca Marcello).
UNIROME1 participants have consolidated experience in the treatment of rare disorders of lipid metabolism with antisense RNA technology. They have developed innovative approaches by using extracellular vesicles (EVs) for delivery targeted RNA therapy and organoid models for several diseases including familial chylomicronemia syndrome (FCS), homozygous familial hypercholesterolemia (HoFH), BRAF mutated thyroid cancer, and Amyotrophic Lateral Sclerosis (ALS).

Marcello Arca
Full professor

Valeria Pecce
Researcher RTD-A

Ilenia Minicocci
Researcher RTD-A

Antonio Musarò
Full professor

Gabriella Dobrowolny
Researcher RTD-B

Luca Madaro
Researcher RTD-B

Maurilio Sampaolesi
Full professor

Alessandra Rossi
Researcher RTD-A

Greta Pomanti
Phd student


Antares Vision contributes to the design of quality control methodologies and offers smart data and tools for the digitalization of the process.

Cesare Furlanello
Senior Researcher and Chief Scientific Officer

Alessandro Chiarini
Senior Data Manager and Business Developer

Ivan Radojevic
Software Development Manager

Nemanja Djuricic
Software Developer

Marko Ilic
DevOps engineer


Chiesi Group contributes through its collaboration with Moderna Inc., on identifying RNA drugs most suitable for development and defining technologies for studying RNA drug distribution, with particular emphasis on translating dosage studies conducted in laboratory animals into doses for human use.

Giancarlo Aquino
Senior scientist

Alessandro Fioni
Senior scientist

Nicola Cesari
Senior scientist

Mirko Milioli
Senior scientist

Paola Puccini
Senior scientist

Benedetta Riccardi
Senior scientist

Giorgia Biasini
Junior scientist


Dompé Pharmaceuticals focuses on RNA vaccine immunotoxicology to develop new methods in vitro and in vivo models for immuno-toxicological evaluations, as well as Good Laboratory Practice (GLP) toxicology studies.

Marcello Allegretti
Chief Scientif Officier

Franca Cattani
Head of Biotech Dev. Senior Director

Andrea Aramini
Head of Research & Early Development

Gianluca Bianchini
Medicinal Chemistry Associate Director

Andrea Antonosante
Biotech Analytical Development Specialist

Maria Candida Cesta
Scientific Collaborations & Funding Director

Cinzia D’Ettorre
Funding Senior Specialist

Daniela Rossetti
Biotech Analytical Development Specialist

Lucio De Simone
Biotech Analytical Development Senior


Eurofins Biolabs is a global leader in testing and research services by supporting research through optimizing current analytical procedures and exploring innovative methodologies.

Alessandro Radici
Sub-Regional Business Line Leader BioPharma Product Testing Mediterranean

Stefano Baila
Managing Director Support Biologics

Nicolo Sacchetti
Science and Business Manager

Luigi Barbarossa
Project Leader

Chiara Picotti
Business Unit Manager BioPharma Biologics

Giulia Mancini
Bioassay Laboratory Manager

Simone Bertolacci
Biotech Laboratory Manager

Giuseppe Peddio
Chemical Laboratory Manager